홈페이지 최상단으로 이동

박우정

  • 성명 : 박우정
  • 소속 : 생명과학대학 해양식품공학과
  • 연구분야 : 식품의학유전공학
  • 실험실 : 식품공학 실헙실
  • 전화번호 : 033-640-2857
  • 전자우편 : pwj0505@gwnu.ac.kr

교수님 소개보기

학력

경희대학교 유전공학과 학사 경희대학교 생명공학원 석사​ Cornell University Food science & Technology 박사

경력

2010-2012 Cornell University Nutritional Science Post-doctoral Associate 2014.3-현재 학과장, 강릉원주대 생명과학대학 해양식품공학과 2012.9-2013.6 부단장, 해양바이오 신소재 클러스터 사업단, 강릉원주대학교 2014.8-현재 간사, 한국식품과학회 전통발효식품분과 2015.8- 2015.12 실무위원, The 6th ICOFF (International Conference on Food Factors) 2014.2-2015.01 홍보간사, 한국유산균학회 홍보간사 2014.2-현재 편집위원, MBL(한국 미생물 생명공학회)지 2013.8-현재 운영위원, 동해안생명과학연구소, 강릉원주대학교 2014.9-현재 운영위원, 강릉원주대 동해안해양바이오산업창조인재양성 사업단(교육부 CK-I 사업) 2012.9-2013.6 부단장, 해양바이오 신소재 클러스터 사업단, 강릉원주대학교​

전문연구분야

1. 기능성 유전자 스크리닝 및 대량 발현 연구 2. In vivo 마우스 시스템을 이용한 면역 및 생리활성 연구

주요논문

1. Surayot U, Lee JH, Kanongnuch C, Peerapornpisal Y, Park WJ, and You SG, "Structural characterization of sulfated arabinans extracted from Cladophora glomerata Kutzing and their macrophage activation. ”Biosci Biotechnol Biochem 2016 May; 80(5):972-82. 2. Hong YF, Kim H, Kim HS, Park WJ, Kim JY, Chung DK, “Lactobacillus acidophilus K301 inhibits atherogenesis via induction of 24 (S), 25-Epoxycholesterol mediated ABCA1 and ABCG1 production and cholesterol efflux in macrophages.” PLoS One 2016 Apr 27; 11(4): e0154302. 3. Park HK, Park WJ, Lawrence P, and Brenna JT, “Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 α-linolenic acids for FADS2 mediated ∆6-desaturation.” Biochim Biophys Acta 2016 Feb; 1861(2): 91-7. 4. Lee JM, Lee H, and Park WJ* “Desaturases and PUFA Biotechnology”, Nutrients 2016 Jan 4; 8(1). Pii: E23doi: 10.3390/nu8010023. *Corresponding Author 5. Surayot U, Lee JH, Park WJ, and You SG, “Structural characteristics of polysaccharides extracted from Cladophora glomerata Kutzing affecting nitric oxide releasing capacity of RAW 264.7 cells.” Bioactive Carbohydrates and Dietary Fibre. 2016 Jan; 26-31. 6. Hong YF, Ham MS,Park WJ, Kim HG, and Chung DK, “Construction of Human Granulocyte-macrophage Colony-stimulating Factor Expression System Using Lactococcus lactis MG1363.” Food Sci. Biotechnol. 2015 Dec; 24(6): 2145-2149. 7. Kim HG, Kim HS,Park WJ, and Chung DK, “Inhibitory Effect of Lactobacillus plantarum Extracts on HT-29 Colon Cancer Cell Apoptosis Induced by Staphylococcus aureus and Its Alpha-Toxin.” J. Microbiol. Biotechnol. 2015 Nov; 25(11): 1849-1855. 8. Tabarsa M, Shin I, Lee JH, Surayot U,Park WJ, and You SG, “An Immune-enhancing Water-soluble α–glucan from Chlorella vulgaris and Structural Characteristics.” Food Sci. Biotechnol. 24(6): 1933-1941. 9. Park HKPark WJ,(Equally contributed), Kothapalli KSD, and Brenna JT “The fatty acid desaturase 2 (FADS2) gene product catalyzes delta 4-desaturation to yield omega-3 docosahexaenoic acid and omega-6 docosapentaenoic acid in human cells“ FASEB Journal 2015 Sep; 29(9): 3911-9. 10. Lee BH, Nam TG,Park WJ, Kang H, Heo HJ, Chung DK, Kim GH, and Kim D, “Antioxidative and Neuroprotective Effects of Volatile Components in Essential Oils from Chrysanthemum indicum Linne Flowers”, Food Science and Bitechnology. 2015 Apr; 24(2): 717-723 11. Surayot U, Wang J, Seesuriyachan P, Kuntiya A, Tabarsa M, Lee Y, Kim JK, Park WJ, You S“Exopolysaccharides from lactic acid bacteria: structural analysis, molecular weight effect on immunomodulation” In J Bio Macromol 2014 Jul;68: 233-40. 12. Lee HJ, Park WJ*, “Unsaturated Fatty Acids, Desaturases, and Human Health”, J Med Food 2014 Feb; 17(2): 189-97. *Corresponding Author 13. Wijendran V, Downs I, Tyburczy C, Kothapalli KSD, Park WJ, Blank BS, Zimmer JP, Butt CM, Salem N Jr, Brenna JT, “Dietary arachidonic acid and docosahexaenoic acid regulate liver fatty acid desaturase (FADS) alternative transcript expression in suckling piglets, Prostaglandins Leukot Essent Fatty Acids 2013 Oct;89(5):345-50. 14. Reardon HT, Hsieh AT, Park WJ, Kothapalli KSD, Anthony JC, Nathanielsz PW, Brenna JT “Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts.”, Prostaglandins Leukot Essent Fatty Acids 2013 Jan;88(1):15-9. 15. Park WJ, Kothapalli KSD, Reardon HT, Lawrence P, Qian S, and Brenna JT “ Novel fatty acid desaturase 1 isoform potentiate FADS2-mediated eicosanoid precursor biosynthesis”, J Lipid Res 2012 Aug;53(8):1502-12. 16. Reardon HT, Zhang J, Kothapalli KSD, Kim AJ, Park WJ, Brenna JT, “Insertion-Deletions In a FADS2 Intron 1 Conserved Regulatory Locus Control Expression Of Fatty Acid Desaturases 1 and 2 And Modulate Response To Simvastatin.”, Prostaglandins Leukot Essent Fatty Acids 2012 Jul;87(1):25-33. 17. Tyburczy C, Kothapalli KSD, Park WJ, Blank BS, Liu Y-C, Nauroth JM, Zimmer JP, , Salem N Jr, Brenna JT "Growth, clinical chemistry and immune function in domestic piglets fed varying ratios of arachidonic acid and DHA.". British J Nutrition. 2012 Mar; 107(6):809-16. 18. Reardon HT, Park WJ, Zhang J, Lawrence P, Kothapalli KSD, Brenna JT, “Polypyrimidine tract binding protein regulates desaturase alternative splicing and PUFA composition.”, J Lipid Res. 2011 Dec: 52(12):2279-86. 19. Tyburczy C, Kothapalli KSD, Park WJ, Blank BS, Bradford KL, Zimmer JP, Butt CM , Salem N Jr, Brenna JT, “Heart arachidonic acid is uniquely sensitive to dietary AA and DHA content in domestic piglets” , Prostaglandins Leukot Essent Fatty Acids. 2011 Dec; 85(6): 335-43. 20. Park WJ, Kothapalli KSD, Lawrence P, and Brenna JT “FADS2 function loss at the cancer hot spot 11q13 locus diverts lipid signaling precursor synthesis to unusual eicosanoid fatty acids”, PLoS One 2011; 6(11): e28186. Epub 2011 Nov 30. 21. Brenna JT, Kothapalli KSD, Park WJ“Alternative Transcripts of Fatty Acid Desaturase (FADS) Genes”, Prostaglandins Leukot Essent Fatty Acids. 2010 Apr-Jun; 82(4-6):281-5. 22. Park WJ, Reardon HT, Tyburczy C, Kothapalli KSD, and Brenna JT “ Alternative splicing generates a novel FADS2 alternative transcript in baboons.”, Mol Biol Rep. 2010 Jun: 37(5):2403-6. 23. Park WJ, Kothapalli KSD, Reardon HT, Kim LY, and Brenna JT “Novel fatty acid desaturase (FADS3) transcripts generated by alternative splicing.”, Gene. 2009 Oct 1; 446(1):28-34. 24. Park WJ, Kothapalli KSD, Lawrence P, Tyburczy C, and Brenna JT “An alternate pathway to long chain polyunsaturates: The FADS2 gene product ∆8-desaturates 20:2n-6 and 20:3n-3.”, J Lipid Res. 2009 Jun; 50(6):1195-202. 25. Park WJ, Lee KH, Lee JM, Lee HJ, Kim JH, Lee JH, Chang HC, Chung DK, “Characterization of pC7 from Lactobacillus paraplantarum C7 derived from Kimchi and development of lactic acid bacteria-E. coli shuttle vector.”, Plasmid.2004 Sep;52(2):84-8. 26. Lee KH, Park WJ, Kim JY, Kim HG, Lee JM, Kim JH, Park JW, Lee JH, Chung SK, Chung DK, “Development of a monitoring vector for Leuconostoc mesenteroides using the green fluorescent protein gene.”, J Microbiol Biotechnol. 2007 Jul;17(7):1213-6. 27. Jang SJ, Park WJ, Chung SK, Jeong CY, and Chung DK., “New E. coli cloning vector using a cellulase gene (celA) as a screening marker.”, Biotechniques, 2001 Nov;31(5):1064-1068.

학회활동

ISSFAL (International Society for the Study of Fatty acids & Lipids), Member American Society of Human Genetics, Member American Society of Nutrition (Experimental Biology), Member 한국 유산균학회 (홍보간사) 한국 식품과학회 (정회원) 한국 식품영양과학회 (정회원) 한국 식품저장유통학회 (정회원) 한국 미생물생명공학회지 (편집위원)

수상

New Investigator award granted by ISSFAL (International Society for the Study of Fatty acids & Lipids) 2008 Conference Committee, Kansas City, Missouri